FEATURE NAME	FEATURE SET
qc_time_missing	QC-ONLY	Missing TIME/SS channels
qc_singlet_missing	QC-ONLY	Missing singlet channels
flag_total_event_ge_500k	QC-ONLY	Tier-A definition flag
flag_low_pc_purity	QC-ONLY	Low PC purity flag (audit/sensitivity)
pc_gate_missing_markers	QC-ONLY	PC gate feasibility flag
pc_gate_too_small	QC-ONLY	PC count below minimum threshold
flag_low_aPC_lt20	QC-ONLY	Below LoD flag (<20 aPC)
flag_meets_lod	QC-ONLY	Meets LoD flag (>=20 aPC)
flag_meets_loq	QC-ONLY	Meets LoQ flag (>=50 aPC)
flag_missing_CD27	QC-ONLY	CD27 missing indicator
n_events_post_qc	MAIN + EXTENDED	Effective event count after QC
qc_time_frac_kept	MAIN + EXTENDED	Fraction retained after time/SS QC (key reliability)
qc_singlet_frac_kept	MAIN + EXTENDED	Fraction retained after singlet QC
pc_count	MAIN + EXTENDED	PC count (post-QC)
pc_purity	MAIN + EXTENDED	PC fraction among post-QC events
apc_gate1_count	MAIN + EXTENDED	Canonical aPC gate (CD19- CD56+)
apc_union_count	MAIN + EXTENDED	Final aPC count (union)
apc_jaccard_agreement	MAIN + EXTENDED	Gate agreement (intersection/union)
apc_percent_pc	MAIN + EXTENDED	aPC fraction among PCs (strong biology)
n_tier3_available	MAIN + EXTENDED	Number of available tier-3 markers (CD27/CD81/CD200)
aberrancy_total_score	MAIN + EXTENDED	Composite aberrancy depth score
cd19_neg_fraction_in_PC	MAIN + EXTENDED	Key malignant signature
cd56_pos_fraction_in_cd19neg_PC	MAIN + EXTENDED	Secondary malignant signature
pc_CD19_median	MAIN + EXTENDED	PC CD19 level (normal vs loss)
pc_CD56_median	MAIN + EXTENDED	PC CD56 level (aberrancy)
apc_CD19_median	MAIN + EXTENDED	aPC CD19 loss central tendency
apc_CD56_median	MAIN + EXTENDED	aPC CD56 gain central tendency
n_events_observed	EXTENDED	Raw event count (pre-QC); usually redundant with post-QC
qc_time_bad_bins	EXTENDED	Count of excluded time bins (instability marker)
qc_time_ss_temporal_cv	EXTENDED	Temporal SS-INT variability (drift indicator)
apc_gate2_count	EXTENDED	Tier-3 supported aPC gate
apc_intersection_count	EXTENDED	High-confidence aPC overlap (intersection)
apc_percent_total	EXTENDED	aPC fraction among post-QC events
n_missing_tier3_markers	EXTENDED	Missing tier-3 markers count
tier3_ge2_fraction_in_cd19neg_PC	EXTENDED	Tier-3 depth fraction (>=2 aberrancies)
pc_CD38_median	EXTENDED	PC marker central tendency (anchor)
pc_CD38_iqr	EXTENDED	PC marker heterogeneity (anchor)
pc_CD138_median	EXTENDED	PC marker central tendency (anchor)
pc_CD138_iqr	EXTENDED	PC marker heterogeneity (anchor)
pc_CD45_median	EXTENDED	PC CD45 central tendency
pc_CD45_iqr	EXTENDED	PC CD45 heterogeneity
pc_CD19_iqr	EXTENDED	PC CD19 heterogeneity (bimodality proxy)
pc_CD56_iqr	EXTENDED	PC CD56 heterogeneity
pc_CD27_median	EXTENDED	PC CD27 differentiation marker
pc_CD27_iqr	EXTENDED	PC CD27 heterogeneity
pc_CD81_median	EXTENDED	PC CD81 maturation marker
pc_CD81_iqr	EXTENDED	PC CD81 heterogeneity
pc_CD200_median	EXTENDED	PC CD200 activation marker
pc_CD200_iqr	EXTENDED	PC CD200 heterogeneity
apc_CD38_median	EXTENDED	aPC CD38 level (anchor)
apc_CD38_iqr	EXTENDED	aPC CD38 heterogeneity
apc_CD138_median	EXTENDED	aPC CD138 level (anchor)
apc_CD138_iqr	EXTENDED	aPC CD138 heterogeneity
apc_CD45_median	EXTENDED	aPC CD45 level
apc_CD45_iqr	EXTENDED	aPC CD45 heterogeneity
apc_CD19_iqr	EXTENDED	aPC CD19 heterogeneity
apc_CD56_iqr	EXTENDED	aPC CD56 heterogeneity
apc_CD27_median	EXTENDED	aPC CD27 differentiation marker
apc_CD27_iqr	EXTENDED	aPC CD27 heterogeneity
apc_CD81_median	EXTENDED	aPC CD81 maturation marker
apc_CD81_iqr	EXTENDED	aPC CD81 heterogeneity
apc_CD200_median	EXTENDED	aPC CD200 activation marker
apc_CD200_iqr	EXTENDED	aPC CD200 heterogeneity
pc_spearman_cd19_cd56	EXTENDED	PC co-expression pattern
pc_spearman_cd27_cd81	EXTENDED	Differentiation coherence pattern